All About Endometriosis

Endometriosis is something that’s not curable, and it’s a gynecological issue that involves tissue that’s near the womb lining growing outside of the womb in different parts. It mostly effects the reproductive system, but also is something that’s commonly found in the bladder, bowel, and even sometimes in the CNS, heart, and lungs. It can be debilitating, and also may cause infertility, along with menstrual cycle control. 

The Problem with Endometriosis 

The thing with endometriosis is something that’s not officially diagnosed, but about 10-15% of women in the world deal with this, and it’s common in those who suffer from pelvic pain that’s chronic. 

There are many who get hospitalized for this, and it can impact your life quality, the activities that you do, your sexual and physical functions, your relationships, your ability to be productive and also et an education, and also will impact your well-being and your mental health too. It also can make it harder for you to achieve the goals that you want to have. 

The pain that comes with this does show itself in a myriad of ways. Some women have pain that’s really hard for them to have sex. Others have cramps that are really bad, or extreme abdominal pain right after and before their menstrual cycles. Some of them have lower back and pelvic pain on the regular, while others may have bowel movements that are incredibly painful. There are even women who experience every single one of these symptoms, which makes it even harder for them to live their lives. It can even cause vomiting and fainting in a lot of cases. 

The Cause 

The thing is, it’s still unknown, and some do theorize that the genetics, your environment, and the immune system you have may be a part of this. Some of them may also have a large sensitivity that comes with pain, and they might react to stimuli that’s not painful like it is, which is something that indicates neuropathy in a lot of cases. Sometimes, this is due to the release of serotonin due to the endometrial tissue invasion, or it may be caused by prostaglandins, histamines, or even nerve issues especially the growth in some of the immune cells. 

The treatments 

Currently, the treatments include NSAIDs, and also other drugs and contraceptives. You may get a laparoscopy or a laparotomy which is a keyhole surgery. However, there is usually still pain. There are some treatments which include utilizing gonadotropin-releasing hormones through a three-month period, but it does cause major side effects. 

There is also some treatments that purport vagus nerve stimulation and treatments. An emerging one, is cannabis, since it can help with the symptoms, mitigating these. While it may not get rid of the problem, it does help with the pain that’s associated with this. This is due to the ECS, and the way that it regulates everything. There are different ways for it to bind, and it also offers signals to different pathways. It’s also responsible for the reproductive organs and systems, managing the regulations of this to help you feel better and maintain homeostasis. 

Some studies even found that endometriosis actually does inhibit these receptors, and also does activate your TRPV1 receptors, which are responsible for pain and inflammation. It’s something that’s also responsible for controlling the proliferation, migration of your cells, and also the interactions with various hormones. There is some possibility that this may be a part of also ensuring that people feel better, and the treatment of endometriosis, however there aren’t a ton of human studies for it.